Munaza Javed, Muhammad Atif Qureshi, Muhammad Naeem Akhtar, Tuba Tariq, Osama Habib, Ramsha Jabbar.
Correlation of Clinical Severity of COVID-19 Infection with Computed Tomography Severity Score in patients Presenting to a Tertiary Care Hospital of Lahore.
J Sharif Med Dent Coll Jan ;08(1):13-6.

Objective: To correlate the clinical severity of COVID-19 infection with computed tomography severity score (CTSS) in a tertiary care hospital of Lahore. Methodology: This retrospective descriptive observational study was conducted at Chaudhary Muhammad Akram Teaching Hospital, Lahore. One hundred and sixty six real-time polymerase chain reaction (RT-PCR) positive COVID-19 patients were enrolled in this study. Clinical COVID-19 disease severity was classified into asymptomatic, symptomatic, severe, and critical disease. A 25 point computed tomography (CT) severity score was utilized to classify the disease as mild, moderate, and severe. Statistical Package for Social Sciences (SPSS) version 20 was used for statistical analysis. The association between clinical severity of COVID-19 infections was studied with CTSS by applying Kendall's tau-b correlation coefficient. Results: Out of the 166 patients, 91(55%) were males while 75(45%) were females. The mean age was 58.09+/-15 years and its range was 20 to 90 years. A statistically significant positive association (tau-b=0.615 and p=0.01) was observed between the clinical severity of COVID-19 infection and CTSS. Conclusion: A positive association exists between the severity of COVID-19 infection and CT severity score. Keywords: COVID-19. High-resolution computed tomography. Real-time polymerase chain reaction.

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