Shabab Hussain, Khan Karim Afridi, Viqar Aslam, Mohammad Nasir, Fazal Ahmad.
Early complications following modified radical mastectomy in patients with breast..
Professional Med J Jan ;30(6):684-8.

Objective: To investigate the early complications, associated comorbidities and risk factors associated with modified radical mastectomy in patients suffering from breast cancer. Study Design: Prospective Cohort study. Setting: Department of Surgery, Khyber Medical University, Institute of Medical Sciences, District Headquarter Hospital, Kohat. Period: January 2021 to December 2022. Material & Methods: A total of 65 patients diagnosed with breast cancer who were planned to undergone through radical mastectomy during the study period were analyzed. Demographical and clinical characteristics of all patients were noted. Early complications, associated comorbidities and related risk factors were recorded. Results: In a total of 65 patients, the mean age was 47±13 years (ranging 50-65 years). At the time of enrollment, 25 (38.5%) patients had painful lump in their breasts while remaining 40 (47.7%) patients reported that they were had swelling in their axillary region. There were 30 (46.2%) patients who had had stage-III breast cancer whereas other 34 (52.3%) were suffering from stage-II breast cancer. Formation of seroma was most commonly associated complication reported in 30 (46.2%) patients whereas 10 (15.4%) patients reported infections of wound. Twenty (30.8%) patients reported that they were having pain on the site of surgery along with paresthesia on the medial side of arm. Five (7.7%) patients had associated diabetes while 8 (12.3%) patients were overweight with their body mass index (BMI) value between 25-29.9 kg/m2. Nine 9 (13.8%) patients were hypertensive. Conclusion: Most common early complications associated with modified radical mastectomy included infection of the surgical site, paresthesia and pain.

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