Aliya Batool, Aliya Batool, Sadaf Khalid.
Establishing and Sustaining a Peadiatric Bone Marrow Transplant Program in Developing Countries.
J Islamabad Med Dent Coll Jan ;12(1):1-3.

Introduction: Bone marrow transplantation (BMT) is an established treatment modality for various Pediatric malignant and nonmalignant hematological diseases such as leukemia, Thalassemia major, Sickle cell disease and bone marrow failure syndrome1. For low-risk patients of sickle cell anemia and Thalassemia, BMT can cure 85% of the cases and improve the long term Health related quality of life,2,3 whereas for high risk malignancies and marrow failure syndromes, BMT is the only lifesaving option. Thalassemia major patients would die without transfusions or BMT. However, long term transfusion and optimized chelation therapy is highly challenging for many developing countries, where this disease is prevalent causing unsustainable health burden. Bone marrow transplantation should be considered the primary treatment of choice in the presence of suitable donor 4 Patient`s condition at the time of transplant is a major determinant of outcome, therefore close association between referral centers and BMT services is necessary.5

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