Arfa Qasim, Lal Rehman, Iram Bokhari, Farrukh Javeed, Haris Hamid, Rubab Qadir.
Management and Outcome of Severe Traumatic Brain Injury.
Pak J Neuro Surg Jan ;27(2):148-56.

Objective: To assess the management of patients with severe traumatic brain injury and their outcomes. Materials and Methods: A prospective observational study was conducted at the Department of Neurosurgery of a tertiary care hospital. Our study included 279 patients in total. After meeting the requirements for inclusion, the patient`s baseline information, such as age, gender, arrival GCS, and outcome, were noted. Three months of post-trauma observation were employed to assess the outcome. SPSS version 22.0 was used to evaluate the data obtained. Results: According to our study out of the total, 118 (42.3%) patients with severe TBI showed good outcomes while 161 (57.7%) showed poor outcomes at 3 months. In our study, the arrival GCS and arrival pupillary reactivity were statistically significant outcome factors (p = 0.040 and 0.010 respectively). Overall mortality was 35.13% (98) at 3 months. Conclusion: Patients presenting with severe TBI have high morbidity and mortality. Arrival GCS and pupillary reaction were important factors to significantly alter the outcome.

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