Arshad Ullah Afridi, Rabia Zaman Khan, Umair Wahab, Ali Nasir, Zubair Ahmed, Sarwat Iqbal.
Using Intranasal Corticosteroids and Oral Antihistamines to Treat Allergic Rhinitis: a Comparison of the Mean Total Nasal Symptom Score.
Annals Punjab Med Coll Jan ;17(3):358-60.

Background: Allergic rhinitis (AR) is a global public health issue. The disease is a leading cause of death and disabilities globally. Objective: To compare the mean total nasal symptom score using intranasal corticosteroids with oral anti-histamine in management of allergic rhinitis. Study Design: Randomized controlled trial. Settings: Department of ENT, Shalamar Medical and Dental College/ Shalamar Hospital, Lahore Pakistan. Duration: 1st January 2023 to 30 June 2023. Methods: 100 cases equally divided in two groups A&B, Intranasal corticosteroids were administered in Group A and oral anti-histamine in Group B cases, The final evaluation was done after 4 weeks of treatment. Results: Comparison of mean total nasal symptom score using intranasal corticosteroids with oral anti-histamine in management of allergic rhinitis shows that 1.51 +- 0.37 score in Group-A and 1.27 +- 0.11 score in Group-B, (p-value < 0.05). Conclusion: We found that the use of intranasal corticosteroids resulted in a substantially reduced mean total nasal symptom score compared to the use of oral anti-histamine in the treatment of allergic rhinitis.

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