Abdul Hamid Chohedri, Behzad Maghsoudi, Muhammad Mahmodi.
Propofol Alfentanil intubation; without muscle relaxant in young adult males.
Professional Med J Jan ;11(2):164-70.

Objectives: To assess the efficacy of propofol & alfentanil without muscle relaxant in young adults. Design: Prospective double-blind study. Setting: Shiraz University of Medical Sciences, (Khalili teaching hospital Shiraz Iran), Period: Aug 2002 to Apr 2003 Material and Methods: 75 non-athlete adult males scheduled for elective surgery were randomly divided to receive either succinylcholine 1.5mg/kg (group S), alfentanil 40µg/kg (A-40) or alfentanil 30µg/kg (A-30) in combination with propofol 2.5mg/kg to induce anesthesia. Results: Hemodynamic responses and intubating conditions were compared between the three groups. In group S marked increase in MAP and HR occurred after intubation but A-40 and A-30 patients had subtle changes (p<0.001). Intubating condition was acceptable in all patients of group S and A-40, but 7 of A-30 group had significant limb movement after intubation. Conclusions: Alfentanil 40 µg/kg & propofol 2.5mg/kg could provide favourable intubating condition in young adult males.

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