Mulazim Hussain Bukhari, Abbas Iqbal, Muhammad Nasir Iqbal, Sarosh Majid, Yasmeen Abbad, Abdul Majeed Chaudhary, Eyad Hassan Kamel, Tahseen M, Naveed I A, Chaudhary N A.
Role of Bioenergy of specific (Si02) of Madina Munawra on chemically induced Carcinogenesis in Albino mice by protecting mutation of p53.
Ann King Edward Med Uni Jan ;10(3):236-40.

Background: This was conjoint to introduce a free and spiritual alternative medicine in the field of oncology by Saudi Arabian and Pakistani Doctors. Objective: To see the preventive and therapeutic role of Bioenergy of specific (Si02) from the earth of Madina Munawra on the mutation of p53 in chemically induced c arcinogenesis in albino rats. Design: An experiment study on skin and breast of albino rats. Place and Duration: The study was carried out at the animal house of Postgraduate Medical institute and King Edward Medical College University, Lahore. It was conducted for 20 weeks for preventive and 10 weeks for therapeutic groups. Material and Methods: 25 albino mice (male and female) were selected for this study. These animals were dived into five groups (A-F), five animals in each. DMBA and TPA (chemical carcinogens) were given to produce the cancer. Bioenergy of Specific SiO2 (taken from the earth of Madina Munawra) was orally and parentally given before giving chemical carcinogens to see its preventive and was given parentally for its therapeutic roles. p53 was detected in all animals. Results: In-group "A" no lesions were produced. In-group B all animals developed skin ulcer. One animal developed papilloma; one Intra epithelial Squamous cell carcinoma and three developed invasive Squamous cell carcinomas. In-group "C" four animals developed lump breast and were invasive ductal carcinomas. Groups "D” and "E" were preventive groups and no malignancy was seen in group D while only one animal developed tubular adenoma breast in group E. Value of mutated proteins p53 was higher in group "B & C" as compared to group A, D, E (P<0.05). Furthermore there was no side effect seen in any animal.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com