Shafique Ahmed, Qazi Masroor Ali, Tariq Ashraf, Muhammad Muzafar Gulzar.
Frequency of Dyslipidemia in normotensive diabetics.
Pak J Cardiol Jan ;16(1):14-22.

Objectives: As diabetes mellitus has been declared CHD equivalent we conducted the study with the idea of the presence of clustering of risk factors. These risk factors may appear mild when considered individually, but when added together, they can raise the risk for heart disease significantly. We specially looked the level of various fractions of lipid -in -type 1-and type 2 diabetes mellitus. Methods: This cross sectional comparative study was conducted on 100 diabetic patients (50 patients of type-1 and 50 patients of type-2 diabetes mellitus) selected by convenience, who presented in OPD, Department of Medicine, Bahawal Victoria Hospital, Bahawalpur and Qazi Diabetic Clinic located in the premises of Medical Colony Bahawalpur. Study included diabetic patients of all groups and from both sexes. Patients with at least one year history of diabetes mellitus. Results: Among the 100 patients suffering from diabetes mellitus, 68 (68%) were males and 32 (32%) were females. Having 18 to 60 years, in type 1 average age 39.18±9.86, in type 2 average age was 53.64±9.95 years. Level of serum total cholesterol was 211.91±40.19 mg% in type 1, 229.54±55.60 mg% in type 2. Level of serum triglycerides was 217±62.34 mg% in type 1 and it was 352.54±181.47 mg% in type 2. Level of serum LDL-C was 131.82±32.17 mg% in type 1 and 134.08±38.48 mg% in type 2. Level of serum HDL-C was 38.88±3.88 mg% in type 1 and 38,82±3.62 mg% in type-2. Dyslipidemias were more common in female diabetic patients. Duration of diabetes showed linear correlation with dyslipidemias. Conclusion: We found elevated levels of serum triglycerides and total cholesterol, decreased HDL-C and disturbed values of LDL-C in both types of diabetes mellitus. So all the diabetics should be educated about dyslipidemias and their serum lipid levels should be checked regularly. Primary prevention can minimize the complications resulting due to diabetic dyslipidemias.

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