Abdul Zahrah F Hussein, Sarkis K Strak.
Silent myocardial ischemia and microalbuminuria in asymptomatic Type-2 Diabetic patients.
Pak J Med Sci Jan ;22(2):116-21.

Objectives: To detect silent myocardial ischemia (SMI) in asymptomatic type 2 diabetic patients with or without microalbuminuria, and the importance of microalbuminuria as a predictor for diabetic cardiovascular complications. Methods: Sixty asymptomatic patients with type 2 diabetes were included in this study. Thirty (17 males, 13 females) with mean age of 54±8.3 years had microalbuminuria (Group-I) were compared with another thirty (21 males and 9 females) with a mean age of (52±7.8 years) who had normoalbuminuria (Group-II). A maximum symptom-limited treadmill exercise test was used to detect silent ischemia. Results: In Group-I, 9 patients (30%) had SMI, with 6 patients showing SMI at higher work load and 3 at low work load. In Group-II, 2 patients (6.6%) showed SMI, one at high load and another at low load. Conclusions: The prevalence of SMI in asymptomatic microalbuminuric and normalbuminuric type 2 diabetic patients were 30% and 6.6% respectively. Even with a maximum exercise, myocardial ischemia might be completely asymptomatic in type 2 diabetic patients.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com