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Assistant Professor, Department of Ophthalmology Madinah Teaching Hospital Faisalabad.

The purpose of study was to differentiate ischemic central retinal vein occlusion from non ischemic central retinal vein occlusion using homocysteine level as a biochemical marker during early stage of the disease. METHOD: Fasting plasma homocysteine level was measured in 50 patients with unilateral ischemic central retinal vein occlusion and compared with a total of 50 age matched patients with non ischemic central retinal vein occlusion patients and 50 age matched healthy control subjects. RESULTS: Homocysteine level was found significantly increased in ischemic vein occlusion(27.1mmol/l)as compared to non ischemic vein occlusion (14.6 mmol/l) and control (12.8mmol/l) subject.(P< .05).

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