Javed Iqbal.
Upper gastrointestinal bleeding.
Professional Med J Nov ;11(4):406-10.

To determine incidence of different causes of upper Gastrointestinal (UGI) bleeding in reference to UGI endoscopy in one hundred patients and to compare the results with similar studies conducted globally. Design: Prospective, comparative study. Place and duration of Study: The department of medicine, Combined Military Hospital, Peshawar during the period of one year from June 2002 to June 2003. Patients and Methods: First consecutive one hundred patients were selected with symptoms and signs of UGI bleeding and endoscopy was performed within 48 hours of start of symptoms. Results of the study were compared with similar studies conducted at other centers in Pakistan and abroad. Results: Major cause of UGI bleeding was found to be esophageal varices (39%) followed by duodenal ulcer (19%), gastric ulcer (9%), superficial mucosal lesion (20%), neoplasia (4%). In 9% patients no cause of UGI bleeding was found on endoscopy.Conclusion: Major cause of UGI bleeding in our set up is esophageal varices while peptic ulcer is less common compared with western world. This reflects high prevalence of chronic liver disease due to viral hepatitis.

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