Seema Tariq, Shamaila Tanveer, Javaria Nousheen.
Comparison of management outcome of induction of labor with expectant management for term prelabor rupture of membranes.
Pak Armed Forces Med J Nov ;61(3):466-9.

Objective: To compare the management outcome of induction of labor with expectant management in patients with term prelabor rupture of membranes (PROM). Study Design: Randomised control trial (RCT) Place and Duration of Study: Department of Obstetrics & Gynaecology Combined Military Hospital Gujranwala, and Department of Obstetrics & Gynaecology Combined Military Hospital Peshawar, from Dec 2006 to June 2008. Patients and Methods: The study was carried in maternity wards and labour rooms of both the hospitals. One hundred and fifty patients fulfilling the inclusion criteria were selected for this study. They were divided into two groups (A and B, 75 each). Patients in group A were induced with tablet prostaglandin E2 placed in posterior vaginal fornix. Group B patients were managed expectantly for 24 hours. Fetal heart rate was monitored one hourly and maternal vital signs were monitored six hourly. Results: The mean duration between PROM to onset of active labor in group A was 8.6±1.7 hours and in group B was 9.3±1.2 hours. The mean duration between PROM to delivery in group A was 16.2±1.5 hours and in group B was 21.9±1.2 hours. In group A, 68 (90.7%) patients delivered by SVD and 7 (9.3%) patients by LSCS. In group B, 67 (89.3%) patients delivered by SVD and 8 (10.7%) patients by LSCS. In group A, 6 (8%) patients developed chorioamnionitis and 10 (13.3%) patients in group B. In group A, there were 3 (4%) cases of neonatal sepsis and 4 (5.3%) patients in group B. Conclusion: Management outcome of induction of labor in term prelabor rupture of membranes is better than expectant management.

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