Ahsan Ul Wadood, Aziz Ur Rehman, Usman Masud, Jamil A Mirza, N J Sahibzada, Aziz ur Rehman.
Helicobacter associated Gastritis a clinicopathological study at Quetta.
Biomedica Nov ;13(2):57-9.

This study was carried out to find the prevalence of Helicobacter Pylori in the gastric biopsies of the patients suffering from dyspepsia. A total of 105 patients age 16 to 78 years were included in the study during the period extending from August 1992 to August 1995. The patients presented with epigastric pain, (73%) retrosternal burning (15.87%) vomiting (7.93%) heaviness after meals (4.76%) burning sensation after meals (3.17%) nausea and haemetemesis (3.16%). Most of the patients had endoscopic evidence of mild to moderate antral gastritis. The endoscopic biopsy material was obtained from the antral part of the stomach, routinely fixed and stained with H and E for detection of type, severity and activity of gastritis. The identification of Helicobacter Pylori was done by Giemsa staining. In a total of 105 cases, chronic superficial gastritis was seen in 81 cases, of these 41 (50.62%) were positive, 40 (49.38%) were negative for Helicobacter Pylori. Thirteen patients had chronic active gastritis, 11 (84.62%) of these patients were positive for Helicobacter Pylori. Chronic follicular gastritis was seen in 11 patients, 10 (90.90%) were positive for Helicobacter Pylori. This study indicates that Helicobacter Pylori is commonly seen in patients with dyspepsia. Moreover there is a positive correlation between severity and activity of gastritis and presence of Helicobacter Pylori in the gastric biopsies. This association was marked in cases of chronic follicular gastritis.

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