Ghulam Rasool Bhurgri, Muhammad Imran Rathore, Muhammad Ali Qazi, Hussain Bux Korijo.
Toxicity of isoniazid (INH); role of biochemical monitoring tests and history of weakness. the management of pulmonary tuberculosis in placebo controlled study.
Professional Med J Dec ;19(1):105-11.

Objective: To compare the untoward effects of isoniazid (inh) and placebo as an anti-tuberculosis therapy in tuberculosis patients. Study Design: Prospective study. Setting: Free T.B Clinic, Muhammad Medical College Hospital Mirpurkhas Sindh. Period: June 2007 to Dec 2007. Patients, Method and Results: Patients were selected with filling of consent forms from free T.B Clinic. Prospective study of adverse effects of INH Isoniazid in tuberculosis treatment. Conclusions: It is concluded like other anti-biotics, Isoniazid must be carefully, mentioned in combination therapy of Anti-Tuberculosis Therapy. The major side effects are those giving rise to serious health hazards, require discontinuation of the drug and referral to chest physician.

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