Saber Mohammad, Sanaullah Khan, Zaman Shah, Sadia Sethi, Lal Mohammad, Badar Mahmood.
Comparison of outcome of Dacryocystorhinostomy with Intubation against Dacryocystorhinostomy with Mitomycin-C (MMC) application Intraoperatively.
Ophthalmol Update Nov ;12(3):175-8.

Objective: To compare the surgical outcome of Dacryocystorhinostomy (DCR) With Intubation against Dacryocystorhinostomy with Mitomycin C (MMC) application in patients of nasolacrimal duct blockage (NLDB). Material and Methods: This study was conducted in Eye A ward ophthalmology department Khyber teaching Hospital, Peshawar from 1st January 2011 to 30th June 2012. This prospective comparative study was performed on 100 patients who presented with CDC. All patients were equally and randomly divided into two groups. In Group A patients underwent DCR with intubation while in group B DCR with MMC application intra-operatively for 5 minutes. Patients were followed for 06 months. The main outcomes of surgery were on the basis of assessment of regurgitation and the patency of lacrimal drainage system. Results: 100 patients of CDC included in this study. Out of 50 patients in group A, 46 (92%) patients remained symptom free whereas, 4 (8%) showed failed syringing with positive regurgitation test at the end of 6 months. However, out of the 50 patients in-group B, 44 (88%) patients remained symptom free and 6 (12%) showed failed syringing with positive regurgitation test at the end of six months. Conclusion: Silicon tube and MMC, both yield equally successful results with DCR surgery. However, use of MMC is more cost and time effective than silicon tube and also associated with lesser intra-operative and post-operative complications.

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