Shamaila Ayub, Qurat-ul Ain Anwar, Omer Bin Khalid Jamil, Yabinda Sahrish, Shafaq Naseer, Farhan Zaheer.
SSI after appendectomy: Comparison of local irrigation with antibiotic solution versus saline.
Pak J Surg Nov ;36(2):118-20.

Objective: To compare incidence of surgical site infection after appendectomy wound irrigation with regular saline solution and imipenem solution. Material and Methods: This was a prospective randomized control trial conducted at Civil Hospital, Karachi. A total number of 72-patients with acute appendicitis who underwent appendectomy were included in the study and randomized into two groups. In group one at closure wound was irrigated with normal saline while second group was irrigated with imipenem solution. Post-operatively patients were observed for surgical site infection, deep abscess formation. Results: Wounds irrigated with imipenem solution showed reduced rates of surgical infection when compared to saline irrigation only (p<0.05) Conclusion: Imipenem solution irrigation is helpful to reduce wound infection after appendectomy. It is an easy to perform and can also reduce healthcare costs and patients` misery due to infection.

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