Nouman Noor, Hasan Mujtaba, Sadaf Humayoun, Muhammad Farooq Umer, Muhammad Mohsin Javaid, Arfa Rehman.
Comparison of Endodontic Pain observed with Sodium Hypochloride, Hydrogen peroxide and Norman Saline based Root canal irrigants.
Ann Pak Inst Med Sci Nov ;18(1):3-8.

Objective: To compare frequency and intensity of endodontic pain with sodium hypochlorite, hydrogen peroxide and normal saline groups. Method:105 subjects were randomly allocated to 3 study arms. Group A (Sodium Hypochlorite), Group B (Hydrogen Peroxide) & Group C (Normal saline).Data regarding endodontic pain was recorded by asking the patient to mark on the Visual Analogue Scale (VAS) according to the severity of pain on the proforma provided. Results: The minimum Intensity of pain was 0 and maximum was 10 with mean and standard deviation were 3.43  3.576 VAS. Endodontic pain was present in 12/35 (34.3%), 24/35 (68.6%), 30/35 (85%) patients of Group’s A, B, C respectively. Significant difference between groups with respect to Intensity of pain (VAS) was shown by one-way ANOVA. For Group A the Intensity of pain (VAS) was 82.38  4.34 and for Group B, C the Intensity of pain (VAS) were 4.37  3.456 and 6.11  3.197 respectively. Conclusions: Sodium Hypochlorite was much better than Hydrogen peroxide and normal saline in the management of endodontic pain in terms of incidence and intensity.

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