Abdul Najeeb Khan, Akbar Khoja, Khemomal A Karira, Manohar Lal.
Gender difference in haemoglobin / hematocrit levels among patients with various degrees of chronic renal insufficiency.
Med Channel Jan ;12(1):29-32.

OBJECTIVE: To observe the gender difference in hemoglobin/hematocrit levels among patients with various degrees of chronic renal insufficiency. DESIGN: A cross-sectional analytical study. Place and Duration of Study: Department of Physiology, BMSI, JPMC, Karachi, in collaboration with Department of Nephrology, JPMC, Karachi. SUBJECTS AND METHODS: The study included 150 subjects, distributed into five groups of 30 subjects each. First group (control) comprising of normal subjects (Cr.Cl >90 ml/min) and remaining four groups [group II (CrCl 60-90 ml/min), group III (CrCl 30-59 ml/min, group IV (CrCl 15-29 ml/min) and group IV (CrCl <15 ml/min)], comprising of patients with increasing severity of the renal insufficiency. Half of the subjects in each group were males. Their hemoglobin and hematocrit levels were analyzed and were statistically compared. RESULTS: As compared to control group, there was a 6.85%, 11.46%, 29.09% and 49.93% decrease in hemoglobin levels in case of males versus 5.15%, 9.24%, 24.24% and 49.0% decrease in case of females when subjects o -group II, III, iv and V were taken into consideration. Similarly, there was 8.45%, 18.13%, 29.47% and 54.0% decrease in hematocrit levels in case of males versus 4.71%, 11.31%, 22.58% and 50.98% decrease in case of females, in the same order. Conclusion: There is a slight gender difference in hemoglobin and hematocrit levels among patients with various degrees of chronic renal insufficiency.

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