Syed Mosaddaque Iqbal, Syed Iqbal Hussain.
Surgical management of Juvenile Nasopharyngeal Angiofibroma, with and without pre-operative Embolization. A comparative analysis.
Med Channel Jan ;12(1):68-70.

OBJECTIVE:To compare the outcome of surgical excision of juvenile nasopharyngeal fibroma (JNF) with & without pre-operative embolization. DESIGN: A descriptive study. PLACE & DURATION: Conducted at departments of Otolaryngology of Peoples Medical College, Nawabshah & Jinnah Post Graduate Medical Centre Karachi between Jan: 1997 to Dec:1999. PATIENTS & METHODS: 23 cases with high clinical and radiological (C.T scan) indices of suspicion of nasopharyngeal angiofibroma were included in this study. Patients were divided into two groups (A&B). Group A comprising of 10 patients who underwent pre-operative embolization. Group B comprising of 13 patients underwent surgery without preoperative embolization. AIMS & OBJECTIVE: 1. To compare pros & cons between surgical procedures with & without pre-operative embolizaion. 2. To compare the chances of recurrence after excision of JNF with and without embolization. RESULTS: Group A indicated 1- Significant reduced blood loss (average 200cc). 2-Recurrence – 3 cases. 3- facial numbness – 1 case. 4- Total cost incurred Rs: 15000. Group B 1- Average blood loss of 2000cc. 2- Recurrence-nil. CONCLUSION: Surgical excision of INF with pre-operative embolization has an advantage of much reduced blood loss during surgery but the rate of recurrence is almost nil in patients who underwent excision of JNF without pre-operative embolisation.

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