Qamar Rizvi.
Comparison of the sensitivity of Typhi Dot test with blood culture in typhoid fever.
Pak J Surg Jan ;23(2):126-8.

Objective: To evaluate the sensitivity of Typhi Dot test in comparison to Blood Culture for the diagnosis of Typhoid Fever in our setup. Design & Duration: Prospective comparative study from February 2004 to February 2005. Setting: S. S. Hospital, Karachi. Patients: Fifty patients who fulfilled the clinical criteria of having Typhoid Fever. Methodology: The data of all the patients was documented, and they were submitted to the Typhi Dot and Blood Culture tests, apart from other routine investigations. Results: Out of the total 50 patients, 47(94%) had their Blood Culture positive for Typhoid bacillus, while in 49 (98%) the Typhi Dot test was positive. Two patients which were found positive on Typhi dot test, gave negative results on Blood Culture. One patient with the signs and symptoms of Typhoid Fever was found neither positive on Typhi Dot test nor upon Blood Culture. Conclusion: There was no significant difference between the results of Blood Culture and Typhi Dot test in the diagnosis of Typhoid Fever. However, Typhi Dot has the advantages of being less expensive and quicker in giving results with excellent sensitivity.

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