Muhammad Khizar Niazi, Mohammad Kashif Hanif, Haseeb Ahmed Khan, Muhammad Amer Yaqub.
Neodymium: Yag; capsulotomy rates following implantation of Pmma and acrylic intraocular lenses.
Professional Med J Jan ;13(4):538-42.

Objective: To evaluate the incidence of posterior capsule opacification after phacoemulsification, between acrylic and polymethylmethacrylate intraocular lenses, by comparing their YAG laser capsulotomy rates. Design: It was a randomized clinical trial. Place and duration of study: Department of Ophthalmology, Military Hospital Rawalpindi, between March 2002-04. Patients and Methods: One hundred and five patients were randomized to receive either a foldable acrylic lens (fifty-two cases), or rigid polymethylmethacrylate lens (fifty-three cases) following phacoemulsification for cataracts. Postoperatively their visual acuities were recorded along with the presence of posterior capsular opacification. Laser capsulotomy was performed if the eyes had lost 2 or more lines of visual acuity. Results: The visual acuity loss at six months in the PMMA group was greater than that in the acrylic group (p< 0.001,Chi-square test). 65% cases exhibiting PCO in the Polymethylmethacrylate group developed it within the first six months, whereas in the acrylic group the development of posterior capsular opacification was seen eighteen months after surgery in 60% cases. Nd: YAG laser capsulotomy was performed in 28% of cases in the PMMA group compared to 6% in the AcrySof group (p < 0.005). Conclusion: Acrylic intraocular lenses is associated with less incidence of posterior capsular opacification and with a significantly reduced rate of YAG laser capsulotomy compared with Polymethylmethacrylate lenses.

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