Zafar Hussain, Muhammad Akram, Aftab Ahmad.
A study of the relationship between body fat distribution and development of hypertension in postmenopausal women.
Pak J Cardiol Jan ;18(1-2):32-7.

Introduction: 75 Pakistan females were involved in this study. They were divided into three groups each consisting of 25-females. The premenopausal group was taken as control group and other two were experimental groups known as early postmenopausal and late postmenopausal groups. Objective: To evaluate the role of body fat distribution in the prediction of atherosclerotic changes leading to coronary heart disease and stroke syndrome in postmenopausal women. Setting: The study was carried out in the Department of Physiology at Postgraduate Medical Institute, Lahore. Duration: August 1999 to October 1999. Methods: Seventy five Pakistan females were involved in this study observing specific inclusion and exclusion criteria. Each group was composed of twenty five subjects. Detailed history was taken on printed proforma with clinical examination. Waist to hip ratio was calculated by the waist and hip circumference measurement in centimeters. The weight wasmeasured by weighing machine. Results: Comparisons were made between mean values of physical parameters with the following schemes: 1. Premenopausal group v/s early postmenopausal group;, 2. Premenopausal group v/s late postmenopausal group;, 3. Early postmenopausal group v/s late postmenopausal group. It was noticed that weight was significantly altered (P < .001) in two comparisons and the WIIR was significantly changed (P < .001) in all the three comparisons. Conclusion: Waist to hip ratio was known to be sensitive marker to atherosclerotic lesions in comparison with simple weight measurement.

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