Muhammad Saeed, Muhammad Saleem Akhtar, Syed Imtiaz Aji.
Relationship between central corneal thickness and infra ocular pressure.
J Rawal Med Coll Jan ;10(2):66-9.

Background: To investigate the relationship between central corneal thickness (CCT) and intra ocular pressure (10P) in Pakistani population. Methods: It was a prospective, non interventional, comparative study which included 200 normal adults in 3 months at the Eye OPD of Rawalpindi General Hospital (RGH) and Mayo Hospital Lahore, (both tertiary care teaching hospitals attached to Rawalpindi Medical College and King Edward Medical University, Lahore respectively). IOP was measured with Goldmann Applanation Tonometer and CCT with contact pachymeter B.V.I France Results: CCT measured were between 430 to 585 microns in males and 457 to 600 microns in females. IOP measured ranged from 8 to 18 mm of Hg in males and 10 to 22 mm of Hg in females. A slight difference in mean CCT was noted between females (513.41 ± 31.17 pm) and males (508.17 ± 32.37 Mm). No statistically significant relationship between the CCT and age could be found in this study. Mean lOP was found higher in people with more CCT. CCT was a significant predictor of IOP. Linear regression analysis showed an increase of 0.62mm Hg with every 15um increase in corneal thickness. Conclusion: Corneal thickness variation must be taken into account while diagnosing patients with Ocular Hypertension (OH) and Normotensive Glaucoma (NTG).

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