Muhammad Aslam, Muhammad Hanif, Shoukat Ishaq, Ashar Alamgir.
Clinical behaviour of pleomorphic adenoma of salivary glands.
J Rawal Med Coll Jan ;10(2):82-5.

Background: Pleomorphic adenoma is the commonest of all benign tumors. It is essentially an epithelial tumor of complex morphology, possessing epithelial and myoepithelial elements arranged in variety of patterns and embedded in a mucopolysaccharide stroma. The objective of the study was to determine the age and sex distribution, frequency of tumour, site of involvement and role of Fine needle aspiration cytology (FNAC) in diagnosis. Methods: The study was conducted in E.N.T. Department, Rawalpindi General Hospital, Rawalpindi. 50 patients diagnosed of Pleomorphic Adenoma who presented to our department from October 2000 to 30th September 2006 were included in the study. FNAC and histopathology were done in all 50 patients. A descriptive study was planned. Results: In this study where a total of 50 patients (20 male and 30 female) were studied, the ratio between female and male was found to be 3:2. Parotid gland was involved in 24 patients (48%), submandibular gland in 12 patients (24%) and minor salivary glands in 14 patients (28%). FNAC was done in all patients and specimen was sent for histopathology. Sensitivity and specificity of FNAC was 87.5% and 60% respectively. Conclusion: This study indicates that parotid gland is the most common site to be involved and pleomorphic adenoma is more common in females. FNAC is highly sensitive in diagnosing cases of pleomorphic adenoma.

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