Tahir Ahmad Mjnir, Nasir Afzal.
C-reactive protein and acute coronary syndrome: comparison of conservative and interventional management.
J Ayub Med Coll Abottabad Jan ;19(2):26-31.

Background: Iflammation plays a key role in the initiation and progression of arthrosclerosis, the most common cause of acute coronary syndrome. C-reactive protein (CRP) that enchances plaque inflammation is synthesized six hours after myocardial infarction. Methods: High sensitivity C-reactive protein was measured by Immnoturbiditory method in 50 healthy controls and 100 patients of acute coronary syndrome on conservative or interventional management. Results: Serum C-reactive protein levels [mg/L ± SEM] at the time of admission were significantly raised in patients of acute coronary syndrome (11.90 ± 2.30) as compared to controls (2.3 ± 0.18) and further increased progressively during 24 hours of follow up period. C-reactive protein levels also increased significantly in patients who underwent interventional management (115.90 ± 7.73) as compared to those who were on conservative management (22.28 ± 5.54). Conclusion: Serum C-reactive protein levels were found to be significantly raised in patients acute coronary syndrome as compared to controls. In addition, patients undergoing interventional management had higher C-reactive protein levels, post intervention, as compared to those on conservative management.

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