Mohammad Hanif Ghani, Mona Humaira, Mohammad Anwer Memon, Hussain Bux, Aslam Aziz Ghouri.
Effect of duration of Diabetes Mellitus on development of microalbuminuria in 103 patients at Liaquat University Of Health Sciences.
Med Channel Jan ;13(4):18-21.

OBJECTIVE: The purpose of our study was to detect the frequency of microalbuminuria & its relation to the duration of diabetes mellitus, whether microalbuminuria develops earlier or late in the natural course of the disease. STUDY DESIGN: Descriptive study. PLACE & DURATION: Liaquat University Hospital Jamshoro. From July 2002 to December 2003. SUBJECTS & MATERIAL: Sample size was 103 patients admitted in the ward or attending the OPD. Data collection procedure was convenient type. After written consent of the patient, the data containing history, examination & laboratory, values of blood sugar (fasting =126mg/dl & 211 postprandial =200 mg/dl( along with other necessary tests, was entered in a proforma. Patients` glycemic control was checked by HbA1C microalbuminuria by Micral 1/ test kit. Microalbunzinuria was confirmed by 24th urine for protein. Data analysis was done by using SPSS 10.0 statistical software. Results were finally checked by test of significance. RESULTS: Among the sample size of 103 patients microalbuminuria was commonly positive in patients with duration of diabetic mellitus from 1 to 12 years (in type 2 DM) & 5 to 16 years (in type 1 DM). P value by chi square method for the correlation between duration of DM & microalbuminuria came out to be 0.001. Microalbuminuria was also positive in significant number (86.95%) of poor glycemic control patients (p=0.005). CONCLUSION: Microalbuminria develops earlier in diabetic population of our study as compare to Europe & USA. Poor glycemic control is a significant risk factor for development of microalbuminuria.

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