Ali Akbar Siyal, Suresh Kumar, Ali Raza Brohi, Qaiser Hussain Naqvi.
Outcome of indirect hperbilirubinemia at NMCH, Nawabshah.
Med Channel Jan ;13(4):57-9.

OBJECTIVE: To detect common causes of indirect hyperbilirubinemia and to make future strategy to prevent hyperbilirubinemia STUDY DESIGN: Prospective study. PLACE & DURATION OF STUDY: Department of pediatrics NMCH Nawabshah from June 2004 to November 2004 over a period of Six months. MATERIAL & METHODS: All newborns having significant indirect hyperbilirubinemia (> 12 mg/dl) irrespective of sex and race, with age ranges from day 1 to 28th day of life, admitted with either jaundice or other problems, had developed jaundice during admission were included. Whole data was entered into computer and statistical analysis was done by SPSS version 10 computer packages. RESULTS: 50 cases were included in this study. Of these 50 cases 22% were preterm and 78% were full term. Male female ratio was found to be 1.5:1. In 35 patients more than one cause was found. Common causes were found to be blood group incompatibility (24%), sepsis (28%), and prematurity (22%). Most of neoborns were in age group of 2-7 days (88%). Over all mortality was 14%. CONCLUSION: Neonatal jaundice is one of the major causes of readmission of newborn to neonatal ICU. In this unknown cause has also contributed major portion because of inadequacy of our diagnostic evaluation and needs further studies for better understanding and control over neonatal jaundice in future

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