Muhammad Al Fareed Zafar, Aftab Mohsin.
Advancement in Treatment of Male Infertility.
Ann King Edward Med Uni Jan ;7(3):224-6.

This study was conducted at Nishtar Hospital, Multan from 1st Jan. 1999 to 30th Sept. 1996 in the Department of Gynaecology and Obstetrics. In all 210 male partners of sub-fertile couples were evaluated. Proper history was taken and they were thoroughly examined. Pre-requisites of semen analysis were observed. Proper criteria for semen analysis were set and 210 semen reports were evaluated according to that criteria. Out of 210 patients, 63 had oligospermia (30%), 21 had azoospermia (10%) These 210 patients were also evaluated on the basis of hormonal profile which included FSH, LH, testosterone, prolactin. 39.7% of Oligospermic men had low testosterone and about 55% azoospermic had low testosterone. Various treatment regimens were tried including Anti-estrogens, gonadotrophins, HCG, bromocriptine, testosterone. Those patients who did not respond to medical treatment were referred for IVF. This study highlights that male factor solely contributes about 30-40 % to sub-fertility and it was being ignored previously but now it is no more an untreatable problem and there are various options and treatments which can be offered to the male patients for subfertility.

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