Yar Mohammad, Muhammad Ahmed, Khalid Masood Gondal, Abdur Rauf Guraya, Salman Akhtar, Abdul Majeed Chaudhry.
Synergistic Gangrene of Abdominal Wall: Our experience at Mayo Hospital, Lahore.
Ann King Edward Med Uni Jan ;7(3):232-4.

In this study 15 patients were selected (out of 920), who developed synergistic gangrene of abdominal wall. They were operated in emergency from July 1997 to June 2001. The most common cause of development of synergistic gangrene was colorectal injury in 11(73.4%) patients due to penetrating wounds. Gangrene developed from the site of penetrating wound. Less common causes include peritonitis in 2(13%) patients, perineal injury one patient (6.6%), criminal abortion one patient (6.6%). Five patients were diabetic. In addition to the general supportive measures, wound debridement was the main basis of treatment. The synergistic gangrene should be prevented by initial wound debridement, if it develops, it has high morbidity and mortality.

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