Khadija N Humayun, Mehnaz Atiq.
Clinical profile and outcome of Cyanotic congenital heart disease in Neonates.
J Coll Physicians Surg Pak Jan ;18(5):290-3.

Objective: To determine the clinical profile and assess the outcome of all neonates diagnosed with cyanotic congenital heart disease. Study Design: A case series. Place and Duration of Study: The Aga Khan University Hospital from January 1998 to December 2000. Patients and Methods: Neonates admitted with diagnosis of cyanotic congenital heart disease were evaluated for clinical diagnosis, survival and mortality. Results: Forty four neonates met the inclusion criteria. Eleven babies (25%) had Tetralogy of Fallot or its variants. Other malformations were d-transposition of great arteries, tricuspid valve anomalies (tricuspid atresia and Ebstein`s anomaly), hypoplastic left heart syndrome, truncus arteriosus, total anomalous pulmonary venous return and complex congenital heart disease like single ventricle. Twenty eight (63.6%) neonates survived and 16 (36.4%) expired during hospital stay. Cause of death was surgical in 2 cases and medical problems in 14 babies. Conclusion: Tetralogy of Fallot or variants was the commonest cyanotic heart disease in neonates with frequency of 27.27%. Majority of neonates with congenital cyanotic heart disease showed survival with appropriate management.

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