Shaikh K R.
Topographic distribution of laryngeal cancer.
J Liaquat Uni Med Health Sci Jan ;6(3):124-6.

OBJECTIVE:To determine the topographical distribution and extent of disease in cases of carcinoma larynx treated in our set up and to compare it with similar studies conducted at other centres. SETTING: Department of ENT (Unit II), Liaquat University Hospital Hyderabad, Sindh – Pakistan from January 1999 to May 2003. METHODS: This study included one hundred cases of carcinoma larynx. Separate proforma for each patient was filled to collect data. Proforma included variables such as personal data, habits, findings on clinical examination, endoscopic findings, and histopathological and radiological reports. RESULTS: One hundred cases of carcinoma larynx were included in this study. Age of the patients varied from 19 to 80 years, but majority of patients belonged to age group between 40 to 60 years. Majority of cases i.e. 92 were male while others female. Male to female ratio was 11:1. The majority of cases belonged to lower socioeconomic class (80%). Most of the male patients were smokers. There were 56% supraglottic, 34% transglottic and 10% glottic tumours. According to the TNM classification of UICC, 54% patients belonged to stage IV, followed by 25% of stage III, 14% of stage II and 7% of stage I. CONCLUSIONS:This study found that majority of patients were male, between 40 to 60 years of age and smokers. Male to female ratio was 11:1 Squamous cell carcinoma was the most common followed by tranglottic tumor, while pure glottic involvement was less common as compared to other studies.

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