Kamran Asghar, Mohammad Zarin, Mohammad Aziz Wazir.
Comparison of operative stress after open & Laparoscopic Cholecystectomy.
Pak J Surg Jan ;24(2):83-6.

Objective: To compare the operative stress after laparoscopic and open cholecystectomy by measuring blood sugar levels of the patients. Design & Duration: Comparative case series from February to July 2007. Setting: Department of Surgery, Unit D, Khyber Teaching Hospital, Peshawar. Patients: A total of 50 patients, aged 20-60 years, including nine males and 41 females with uncomplicated gall stones who underwent open (n-25) and laparoscopic (n-25) cholecystectomy. Pregnant females and patients of other age groups, and those with hepatitis and other co-morbidities were excluded. Methodology: The patients were randomly assigned to the open and laparoscopic groups. The blood samples of the patients were collected at 06 hours and then at 18 hours on the day of surgery, their blood sugar level estimated and the results tabulated and compared. Results: The preoperative blood sugar level of the patients undergoing open cholecystectomy ranged between 57- 93 mg/dl (mean 76.08±3.6) and the postoperative level from 75-143 mg/dl (mean 110.75±6.4); the percentage rise in blood sugar level being 45.5%. In case of laparoscopic cholecystectomy the preoperative blood sugar level ranged between 62-95 mg/dl (mean 78.9±6.4) and the postoperative level from 78-128 mg/dl (mean 97.78±12.8); the percentage rise in blood sugar level being 23.9%. Conclusion: Blood sugar levels were more in patients with open cholecystectomy than those who underwent laparo- scopic cholecystectomy. Hence laparoscopic cholecystectomy results in less prominent stress response and metabolic interference as compared to open cholecystectomy.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com