Qurban Ali Shaikh, Nisar Ahmed Shaikh, Akbar Ali Soomro, Ghulam Shabir Shaikh, Abdul Rasheed Shaikh.
Acute renal failure: an experience at nephro-urology department Chandka Medical College Hospital Larkana.
Professional Med J Jan ;15(2):229-33.

To find out the various causes of acute renal failure (ARF) and its out come in our setting of tertiary Care Hospital in rural areas. Design: A retrospective Study. Setting: Nephro-urology department Chandka Medical College teaching hospital Larkana. Period: From March 1998 to March 2005. Patients & Methods: Review of 294 patients of acute renal failure admitted in Nephro-urology department Chandka Medical College teaching hospital Larkana. Detailed history, physical examination and laboratory data of 294 consecutive patients of acute renal failure were analyzed. Result: 294 patients were included in this study. Among them 149 (51.7%) were in the younger age group (less than 40 years) with dominance of males (1.61 to 1.00 male to female ratio). Major cause of ARF was pre renal, seen in 172 (66.6%) patients, 70 (23.8%) of all cases of acute renal failure had gynecological and obstetrical back ground. Other causes C.V.A in 24 (9.3%), HHD in 14(4.5%). Glomerulonephritis in 22(8.5%),and obstructive uropathy in 16(6.2%). 92 Patients (31.3%) improved on conservative treatment,166(56.5%) needed dialysis and 36(12.2%) left against medical advice. Conclusion: This data reveals that pre renal element is the single most important cause of acute renal failure, in which commonest cause was pregnancy related ARF followed by C.V.A,HHD, glomerulonephrits and obstructive urophathy. Early indentification, referral treatment of pre renal factors, good peri natal care and good therapeutic measures substantially bring down the incidence of acute renal failure. 12.2% patients left against medical advice due to heavy expenses on the treatment and needs NGOs and Government support for treatment of poor patients.

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