Mohammad Hassan Naseri, Bahram Pishgou, Javad Ameli, Esmaeil Babaei, Hamid Reza Taghipour.
Comparison of post-operative neurological complications between on-pump and off-pump coronary artery bypass surgery.
Pak J Med Sci Jan ;25(1):137-41.

Objective: To assess neurological impairment after the off-pump and on-pump techniques in patients with first-time isolated coronary artery bypass graft surgery. Methodology: One hundred twenty patients undergoing first-time isolated coronary artery bypass graft surgery prospectively at Baqiatallah University Hospital, Tehran, Iran were randomised to the off-pump or on-pump technique. Change in NIHSS score was measured at 30 days postoperatively. Results: The on-pump group showed a significantly greater deterioration in scores than the off-pump group. The incidence of TIA at 30 days postoperatively was 15.3% (9 out of 60) in the on-pump group and 5% (3 out of 60) in the off-pump group. (P=0.05). The incidence of Stroke at 30 days postoperatively was 3.4% (2 out of 60) in the off-pump group, while no one from off-pump group suffered from stroke. (P=0.05) Conclusion: Off-pump coronary artery bypass graft surgery results in less neurological impairment than the on-pump technique.

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