Asal Khan Tareen, Abdul Samad Achakzai, Liaquat Cheema, Anwar Ali, Muhammad Rehman.
Comparison of serum lipids, lipoproteins and apolipoproteins in patients undergoing CABG with healthy adults.
Pak Heart J Jan ;40(4):38-46.

To assess the pattern of plasma lipoproteins in CAD patients including comparison between diabetic and non-diabetic subgroups. METHODS: This case control study was conducted at National Institute of Cardiovascular Diseases (NICVD) Karachi on patients admitted for CABG from June, 2000 to June, 2001. A total of 100 patients and 100 healthy subject were enrolled during the study. 38 patients (38%) were diabetic with mean age of 46.16 years and 62 patient (62%) were non-diabetic with mean age of 45.26 years. Serum lipids, apolipoproteins A, apolipoproteins and Lp(a) of each subject were analysed. One way ANOVA and 95% confidence interval for mean wer applied to find the association of CAD with age, BMI, glucose, cholesterol, triacylglycerols, HDL-c, LDL-c; and Lp(a). RESULT: CABG patients had significantly higher blood TAG levels than controls. Similar results were observed fo HDL-c, which was significantly lower when compared with control subjects. Apo-B and Lp(a) in control were significantly lower than both diabetic and non-diabetic CAD patients. The level of Apo-B in diabetic CAD was significantly higher when compared with control subjects.

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