Abdul Rahim Siyal, Sher Muhammad Shaikh, Rafia Balouch, Abdul Waheed Surahio.
Gynecological Cancer: A Histopathological Experiences at Chandka Medical College and Hospital Larkana.
Med Channel Jan ;5(4):15-9.
Gynecological cancer is an important cause of morbidity and mortality in women through out the world. The objective of the present prospective study was to determine the frequency and histopathological pattern of the cancer involving different organs of female genital system. A total of 282 cases were studied during the period of seven years from January 1992 to December 1998. The average age of the patients studied was 46.48 years and the peak age group was in the fourth decade. Three most commonly involved organs were ovary 941.16%), cervix (35.46%) and uterine corpus (14.89%). Three fourth (75.87%) of ovarian tumours were of surface epithelial origin with predominance of poorly differentiated adenocarcinoma. The most common cervical cancer was invasive squamous cell carcinoma (85%) with preponderance of poorly differentiated tumour. The most common tumour of uterine corpus was adenocarcinoma of endometrium whereas squamous cell carcinoma dominated the tumours of vulva and vagina. Frequency pattern was different from that of a USA study where cervical cancer tops the list. And tumours of our group were in more advanced histological grades as compared to the western counterparts.
PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com