Javed Sarwar, Nasreen Gul, Muhammad Idris, Anisur Rehman, Jamila Farid, Muhammad Yasir Adeel.
Seroprevalence of hepatitis B and hepatitis C in health care workers in Abbottabad.
J Ayub Med Coll Abottabad Jan ;20(3):27-9.

Background: Hepatitis B and C viruses (HBV & HCV) are hepatotropic viruses causing viral hepatitis, chronic liver disease and hepatocellular carcinoma. Modes of infection are more or less similar. HBV is vaccine preventable while HCV is not. They are prevalent in different parts of the world including Pakistan. The rate of prevalence varies from region to region and among different population segments. The present study was planned to see the prevalence of HBV & HVC among health care workers in various hospitals of Abbottabad. Method: The study was conducted at the District Headquarter Teaching Hospital Abbottabad over a period of one year on 125 health care workers of different categories and either sex. Brief history was taken from each individual and physical examination was performed. Blood samples were taken for HBV and HC serology. Positive sera were confirmed by 3rd generation ELISA. Results: As much as 8% individuals were positive for HBV or HCV. HBV alone was seen in 3 out of 10 (30%) individuals. HCV alone was also found in 3 out of 10 (30%) individuals. HBV and HCV co-infection was seen in 4 out of 10 (40%) individuals. Dental procedures, needle prick and surgical procedures were found the common risk factors. Blood transfusion was known in 2 out of 10 (20%) individuals. Family history of hepatitis was not positive in any individual. Conclusion: Results of the present study differ from those of the previous studies conducted on health care workers in Pakistan.


USER COMMENTS

Clinically review on this study is beyond my range and scope, however, statically there are some weak areas in this study, first sample size is very small for such kind of studies, specificity should be ruled out in this study, association of disease should be discussed using some strong statistical tools like logistic regression, OR (odds ratio).
Posted by: ibrahim_ap on Jan 2010

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com