Sankha Koley, Atul Salodkar, Sumit Gupta, Arvind Bhanke, Ashish Ujawane, Shazia Bisati.
Ichthyosis bullosa of Siemens sans history of blistering: an interesting case report.
J Pak Assoc Derma Jan ;19(3):171-4.

Ichthyosis bullosa of Siemens (IBS) is a rare disease characterized by superficial blistering, mild epidermal hyperkeratosis over flexural areas and characteristic mauserang phenomenon (moulting).We report an interesting case of IBS in a mentally retarded hypothyroid patient who did not give any history of blistering. Histological examination of specimen from margin of an area exhibiting mauserung phenomenon revealed epidermolytic hyperkeratosis in granular and upper spinous layers. In situations where proper clinical history cannot be elicited, the histopathological findings have paramount importance.

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