Muhammad Munir Rashid, Tamanna Chowdhury, Abida Sultana, Rokeya Begum, Shiropa Islam, Iftekhar Ahmed.
Necrobiotic xanthogranuloma – a case report.
J Pak Assoc Derma Jan ;19(3):175-7.

We report here a 70-year-old lady with multiple large soft yellowish plaques around her eyes for last 10 years. Histopathological evaluation revealed a dense histiocytic infiltrate with hyaline necrobiosis involving the dermis with extension to the subcutis. Multiple large multinucleated giant cells and scattered lymphocytes were seen. Serum protein electrophoresis revealed nonspecific findings. Based on the clinical picture, and histopathology results, a diagnosis of necrobiotic xanthogranuloma was made.

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