Subramanian S, Sankar V, Asha Asokan Manakadan, Sareena Ismail, Andhuvan G.
Formulation and evaluation of cetirizine dihydrochloride orodispersible tablet.
Pak J Pharm Sci Jan ;23(2):232-5.

Cetirizine orodispersible tablets were prepared to achieve quick onset of action and for maximum bioavailability. Tablets were prepared using cetirizine along with camphor and mannitol in the proportion of 1:1:1, 1:1:3, and 1:1:6. The flow property of granules was found to be good for the formulation CZ2 (1:1:3). The hardness and friability of all the formulations were found to be within the standard limit for orodispersible tablets. Disintegration time was found to be rapid in formulation CZ2 (1:1:3).The in vitro dissolution time was found to be 100% in 11 minutes for the formulation CZ2 (1:1:3).

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