Bikha Ram Devrajani, Agha Taj Muhammad, Altaf Ahmed Shaikh, Syed Zulfiquar Ali Shah, Tarachand Devrajani, Thanwar Das.
Frequency of gallstones in patients with diabetes mellitus (a hospital based multidisciplinary study).
Med Channel Jan ;16(2):230-2.

OBJECTIVE: To determine the frequency of gallstones in patients with diabetes mellitus PATIEHTS AND METHODS: This cross sectional type descriptive study was conducted in the department of Medicine and General surgery at Liaquat University Hospital (a tertiary care teaching hospital) Hyderabad and at tertiary care hospital attached with Ghulam Muhammad Maher Medical College from March 2009 to August 2009. All the patients were known cases of diabetes mellitus, of >5 year duration, presented with acute abdominal pain, were further evaluated for the presence of gallstones. The patients were also assessed for their diabetes and serum lipid status. The data was collected, saved and analyzed in SPSS version 10.00 and the frequency and percentage of gallstone in patients with diabetes mellitus was calculated. RESULT: Out of 104 patients with diabetes mellitus, 72(70%) had gallstones, mean age 45.73 ± 6.53, male 24(33%) and female 48(67%) respectively. The upper right part of the abdomen was observed in all 104 subjects, fever in 60/72 (83%) patients, nausea and vomiting in 48/72(67%) patients, loss of appetite in 35/72 (49%) patients, feeling of tired or weakness in 60/72 (83%) patients, headache in 42/72 (58%) patients, chills in 58/72(81%) patients, pain in the back 55/72 (76%) patients, pain under the right shoulder in 38/72 (53%) patients, belching in 45/72 (63%) patients, indigestion in 53/ 72 (74%) patients. The serum cholesterol was raised in 32 patients, low density lipoprotein was elevated in 20 patients and serum triglycerides was raised in 27 patients CONCLUSION: The patients with raised blood glucose level (diabetes mellitus) are more prone to develop gall stones (cholelithiasis).

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