Nousheen Aziz, Sajida Yousfani, Nusrat Nisar, Firdous Mumtaz.
Mgso4 as anticonulsant of choice in eclampsia.
Med Channel May ;16(2):253-5.

OBJECTIVE: To determine the frequency of eclampsia and to evaluate the use of Mg SO4 as an anticonvulsant agent for control of fits and prevention of their recurrence . DESIGN : A descriptive (case series ) study . PLACE AND DURATION OF STUDY : This study was carried out at Department of Obstetric and Gynaecological liaquat University Hospital (LUH ) Hyderabad, from Jan –Dec 2007 . PATIENTS AND METHODS : During the study period Mg SO4 was given to 29 eclamptic women according to set protocol for its use . The recurrence of fits, side effects, maternal and fetal outcome were recorded in a pre-designed proforma . Data gathered was entered and analysed by SPSS version 14. RESULTS : Out of 3327 patients 29 (0.87) had eclampsia . Majority of women were young between 21-29 years of age ( 68.96% ) , primigravida (48.2%) and with duration of pregnancy <35 weeks ( 41.37% ) . Caesarean section was performed in (58.6%), 20 ( 90.9%) delivered live babies while 2 ( 9.0% ) had still birth . Mg SO4 was effective in all patients for control of fits except for 2 patients had recurrent convulsions. One patient had pulmonary oedema and died . CONCLUSION : Mg SO4 was found as a safe and effective anticonvulsant in controlling eclamptic fits, to prevent recurrence of futher fits, the only thing is clinical monitoring of patients for side effects.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com