Irfan Ahmad, Habib Ur Rehman, Javed Iqbal.
Clinical profile and impact of proper treatment in acute organophosphorus pesticide poisoning.
J Sheikh Zayed Med Coll Jan ;1(3):91-3.

Background: Acute poisoning with organophosphorus (OP) pesticides is one of the most common forms of poisoning world wide. It generally results from accidental or intentional ingestion, inhalation or cutaneous exposure. Objective: To determine the demographic & clinical features, management and outcome of patients with acute organophosphorus poisoning. Patients and Methods: This observational study was conducted in medical department of Sheikh Zayed Medical College/Hospital, Rahim Yar Khan from 1st April to 30th September, 2009. Fifty patients above 12 years of age, who presented with acute organophosphorus poisoning, were included in this study. Demographic features, mode and route of poisoning, clinical presentations, management, and outcome were noted. Results: Mean age of 50 patients was 24 ± 6.17 years. Thirty nine (78%) patients were male and 11 (22%) were female. Accidental exposure was present in 13 (26%) patients and suicidal attempt in 37 (74%) patients. Forty eight (96%) patients took OP orally and 2 (4%) were exposed to it through inhalation. Mean time from exposure to presentation in emergency department was 1.68 hours and mean hospital stay was 2.52 days. Three patients with OP poisoning died. Conclusion: OP poisoning is usually suicidal and more common in young males. Prompt treatment ensures low mortality rate.

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