Amir Mohammad, Mohammad Irshad, Behram Khan.
A comparative study of measles complications in vaccinated versus non-vaccinated children.
J Postgrad Med Inst Jan ;25(1):4-8.

Objective: To find out and compare the frequency of measles complications among vaccinated and nonvaccinated children. Methodology: This hospital based cross-sectional comparative study was conducted in Pediatrics Unit, PGMI/LRH, Peshawar All the patients were divided into two groups. In group 1, 100 vaccinated and in group 2, 100 non-vaccinated children were included. Both groups were compared for complications of measles. Results: In group 1, majority (51%) cases were in age range of 1-3 years and in group 2, majority (59%) cases were also in age range of 1-3 years. In group 1, male were 55 (55%) and 45 (45%) were female. In group 2, male were 53 (53%) and 47 (47%) female. In group 1, complications include bronchopneumonia in 49 (49%), upper respiratory tract infection in 39 (39%), diarrhea in 32 (32%), oral ulcer in 31 (31%), dehydration in 15 (15%), otitis media in 10 (10%), malnutrition in 2 (2%), encephalitis in only 1 (1%) case. In group 2, bronchopneumonia in 51 (51%), diarrhea in 50 (50%), upper respiratory tract infection in 24 (24%), oral ulcer in 22 (22%), dehydration in 20 (20%), otitis media in 17 (17%), malnutrition in 12 (12%), and encephalitis in 11 (11%) patients. Conclusion: Nearly 50% of children in both groups were less than 5 years of age. This indicates that many children of this age group are still unprotected. Overall dif erence in vaccinated and unvaccinated groups was statistically significant (P value = 0.001).

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