Yogita Soni, Rajnee.
Effect of cyamopsis tetragonoloba (GUAR) on lipid profile in diabetic and non-diabetic subjects.
J Postgrad Med Inst Jan ;25(3):199-205.

Objectives: To compare the effect of Guar fiber in Roasted and cooked vegetable form on lipid profile in diabetic as well as in normal healthy subjects. Methodology: This study was conducted at Department of Medicine, Sardar Patel Medical College, Bikaner, India on 120 subjects in which 60 were diabetic and 60 non diabetic. Blood samples were withdrawn before and after 15 and 30 days of consumption of 10.0 and 20.0 gm of roasted and cooked guar fiber per day and analyzed for sugar, cholesterol, triglyceride, HDL, LDL and VLDL-cholesterol by standard technique using semi-autoanalyzer. Results: The Blood sugar, cholesterol, triglyceride, LDL and VLDL showed highly significant results (t=4.33 & p<.001)after supplementation of roasted guar fiber for 30 days as compare to that of cooked vegetable guar fiber in normal as well as in diabetic subjects in daily routine diet, Blood sugar level(96.9 ± 2.49%) after 30 days consumption of 20 gm roasted guar fiber per day in normal subjects & in Diabetics (154.3 ±15.38%) where as HDL showed no significant change when 20 gm roasted fiber given for 15 days (49.7±7.10),after 30 days range is (55.5±8.16),p value(p<.05). Conclusions: Roasted guar, as compared to cooked guar, significantly reduces Blood sugar,serum cholesterol,triglyceride,LDL and VLDL level not HDL, in both diabetic and non diabetic adults.Roasted guar fiber diet is beneficial for Diabetic as well as Cardiac patients.

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