Ibrar Hussain, Mahmooda Soni, Bakht Samar Khan, Mohammad Daud Khan.
Basal cell carcinoma presentation, histopathological features and correlation with clinical behaviour.
Pak J Ophthalmol Jan ;27(1):3-7.

Purpose: This study was performed to determine the clinical presentation and histopathological types of basal cell carcinoma of eyelids and correlation with clinical behaviour. Material and Methods: The prospective study was carried out at the Department of Ophthalmology, Postgraduate Medical Institute, Hayatabad Medical Complex, Peshawar from September 2001 to August 2002. Thirty patients (30) with suspected basal cell carcinoma were enrolled from the outpatient department. They were admitted to ward and worked out as detailed history, examination, Lab and radiological examination. In each case biopsy (incisional / excisional) were taken to study its histopathology. Using EPI info 2000 version SPSS program data was entered and analyzed. Results: Mean age of presentation was 55 years with Male: Female (57:43). Clinically the nodular ulcerative type was commonest presentation (36.7%) followed by the nodular type (33.3%) and the third commonest presentation was nodular pigmented (30%). The lower lid was the most frequently affected site (63.3%) followed by the medial canthus (23.33%). The upper lid and lateral canthus were the least involved (6.67%) each. On histological examination the commonest was solid or nodular (56.67%), the second commonest was keratotic (basosquamous) type (13.33%) followed by multifocal (10%), pigmented and adenoid (6.67%) each. Morphoea and the cystic type were the least common (3.33%) each. The margins were well defined in 80% of the solid tumour. Conclusion: Basal cell carcinoma commonly occurs in lower eyelid. Nodular ulcerative is the commonest clinical presentation and the commonest histological presentation was also nodular with peripheral palisading.

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