Mah Muneer Khan, Hamida Begum, Adil Shah Roghani, Mian Asadullah Jan.
Seroma formation in modified radical mastectomy: why, whom and when?.
J Med Sci Jan ;19(1):39-42.

Objectives: The objective was to determine the frequency of seroma formation after modified radical mastectomy and the possible causes. Material and Methods: This descriptive, observational study was done in the Surgical “B” Unit, Khyber Teaching Hospital, Peshawar, Pakistan over a 1 year period (1st November 2005 to 31st Oct 2006). Patients undergoing mastectomy with axillary dissection were selected according to the inclusion/exclusion criteria by convenience method. All the patients were interviewed using a proforma. The data was analyzed using descriptive statistics. Results: Forty two patients, 1 male and 41 female underwent mastectomy and axillary dissection of whom 13 (31%) developed a seroma. Advanced age was significantly associated with seroma formation. Out of 6 (14.3%) hypertensive patients 3(50%) developed a seroma, while amongst the 30 (71.4%) over weight patients, 10(33.3%) developed seroma. There were 9(21.4%) anemic patients of whom 4(44.4%) developed a seroma. Aspiration of seroma was done in 5(38.5%) patients. Recovery was uneventful in all patients. Conclusions: Certain factors might be associated with an increased risk of seroma formation.

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