Shahida Tasneem, Fareeda Naseer, Khanzada Mohammadi, Mah Muneer Khan.
Fine needle aspiration cytology versus histopathology of breast masses.
J Med Sci Jan ;19(1):5-8.

Objective: To evaluate the accuracy of fine needle aspiration (FNAC) of breast masses using histopathology as gold standard. Material and Methods: This study was conducted from January 2007-June 2008 in patients who attended the out patients department of Khyber Teaching Hospital, Peshawar and Mumtaz Surgical Hospital Peshawar. A total of 90 patients with age range 13-80 yrs were included in this study. All patients who had FNAC underwent incisional or excisional biopsy to confirm the diagnosis. All the FNAC smears were categorized according to National Health Services Breast Screening Programme (NHSBSP) 2001-3 criteria into five categories. Results: In our study, the absolute sensitivity was 71.15%, complete sensitivity was 96.15%, specificity was 92.11%, positive predictive value (PPV) for C5 was 100%, PPV for C4 was 90% and for C3 was 66.67%. The false negative (FN) rate was 1.92% and false positive (FP) rate was 0%. The inadequate rate was 4.4%. Conclusion: This diagnostic modality may be suitable for developing countries, because of the simplicity and low cost of the procedure.

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