Saadia Shamsher, Farhat Khanum, Irum Sattar.
Induction of labour with prostaglandins E2.
J Med Sci Jan ;18(3):160-3.

Objectives: To evaluate the role of prostaglandins E2 vaginal pessary for induction of labour in term pregnancy. Material and Methods: This study was carried out at Khyber Teaching Hospital, Peshawar from January 2002 to December 2002. Hundred patients’ primigravida and multigravida at term with different Bishop Scores were induced with prostaglandins E2 vaginal pessary, followed by oxytocin infusion if needed. Once in labour a policy of active management was followed. The duration of induction, induction delivery interval, duration of labour, maternal out come were noted. Results: Total 100 patients were divided into 3 groups according to the bishop scores, 50, 40 and 10 patients in group A, B and C respectively, mostly patients (86%) were delivered vaginally. Eight percent and 6% patients had cesarean section and instrumental delivery respectively. The induction delivery interval, duration of labour was more in group A and B as compared to group C. Only 5% patients developed complications like precipitate labour, hyperstimulation. Three percent cases have failed induction. Conclusion: For a good induction of labour, Prostaglandins E2 should be applied for cervical ripening before start of contraction.

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