M J Asif, Z Iqbal, Z Iqbal (Capt.), F Iqbal.
Acute Leukaemia in Adults: Morphological Profile of 101 Patients.
Ann King Edward Med Uni Jan ;6-4:343-8.

A total of 101 consecutive patients of acute leukaemia were diagnosed in adults (age range 16-74), during a period of 6 1/2 years. These patients included 74 males (73.3%), and 27 females (26.7%) with male/female ratio of 2.74:1. AML was the most frequent type accounting for 73 patients (72.3%), followed by ALL, 25 patients (24.8%) and 3 patients (2.9%) were diagnosed as bilineal leukaemia on morphological and cytochemical grounds. Overall AML/ALL ratio was 2.9:1. Amongst AML, M2 was the most frequent subtype accounting for 67.1%, followed by M4, Ml, M3, M5, MO and M6. Amongst ALL, L2 was the most frequent subtype accounting for 64% followed by L1 and L3. Total cases of acute leukaemia and AML showed a bimodal age related distribution. ALL showed highest incidence in younger adults (age 16-25 years), and a sharp progressive decline in incidence thereafter.

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